Sam Altman, the recently fired (and rehired) chief executive of Open AI, was asked earlier this year by his fellow tech billionaire Patrick Collison what he thought of the risks of synthetic biology. ‘I would like to not have another synthetic pathogen cause a global pandemic. I think we can all agree that wasn’t a great experience,’ he replied. ‘Wasn’t that bad compared to what it could have been, but I’m surprised there has not been more global coordination and I think we should have more of that.’

  • David Gerard@awful.systems
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    this thread appears to have attracted keyword-seeking bad posters. these fine posters have been escorted to the egress and may continue to enjoy their subthreads on other fediverse servers and not this one.

    • self@awful.systems
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      to clear up any confusion: if you’re a drive-by poster we’ve never seen before and you’re posting bullshit covid theories instead of anything related to what we discuss on this instance (Sam Altman being a fucker, for example), we can’t tell you apart from someone keyword searching threads to spread conspiracy bullshit en masse and the very funny part is, we don’t actually care how you got here

      garbage is garbage, don’t post your trash here

        • PsychedSy@sh.itjust.works
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          I didn’t say anything on the topic and I can’t even see the negative ones. I don’t really know how many comments you guys usually get off-instance. I’m curious now if people actually care enough to just monitor shit and say dumb things.

          • self@awful.systems
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            this kind of keyword searching (sometimes via a discord bot or similar for coordination purposes) is ridiculously common — old r/SneerClub was an interesting Petri dish for it, cause you’d get accounts that only post about Urbit or on TheMotte every couple months barging into a SneerClub thread for the first time going “uhhh can you prove to me, whoever the fuck I am, that these people are fascists though?” and it was painfully obvious to everyone else what they were trying to do

          • David Gerard@awful.systemsM
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            i meant that the discussion threads will still be present on non-home servers even as the users are blocked from here

            it lets them have the last word but in a way that means nobody on awful.systems will have to see it

    • Floey@lemm.ee
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      How do you determine if someone is coming across a post because they searched a keyword? I arrived here because I sort by new comments and someone must have just commented.

  • swlabr@awful.systems
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    I would like to not have another synthetic pathogen cause a global pandemic.

    Gonna ignore the urge to sneer at the tinfoil hattery here. See the rest of this comment section for that.

    I think we can all agree that wasn’t a great experience

    Sam, you have a doomsday bunker and a bunch of cash. This was one of your dream scenarios. Don’t pretend like you’re one of us.

    • Charlie Stross@wandering.shop
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      @swlabr He doesn’t have mirrorshade-wearing bodyguard goons wearing collar bombs to keep them in line after civilization collapses. Or a long pork sushi chef. Yet.

      • swlabr@awful.systems
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        Yeah that’s probably what he meant by not a “great experience.” Our billionaire baby boy couldn’t get a nice night’s sleep without his hommes au jus.

      • froztbyte@awful.systems
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        Pro-tip: you can choose not to be a volunteer marketwashing billionaire stan

        Sammyboi isn’t going to give you a hug or a handshake for helping his image

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          Those kinds of comments are also so weird, because the remark was that he has money and a doomsday bunker. Like how do you ignore half that sentence? It wasn’t even long.

          Of course in reality it doesn’t seem Sam has a bunker, it is worse. he actually makes fun of the people with money who have bunkers, I hope Atheartengineer is consistent and also tells Sam his comments are fucked, and that Sam is inconsiderate for making fun of those poor people with money. ;)

          (The latter part of the comment was just me going ‘wait does he even have a doomsday bunker’ it comes from my curiosity and attempts at being funny not some deep seated fight against hypocrisy)

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              The whole bunker/bunkerlikes thing is one of the more evil things the megarich have done. And imho it also points to some very dark futures which causes me to have some feelings re the future which I try not to talk about online (as I don’t think negativity is productive, and I it is very likely they (and via that me too) are wrong, they are idiots after all). But yeah they are not even trying!

      • swlabr@awful.systems
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        hey guy, accounting for the fact that he has overabundant capital and thus has a fundamentally different human experience to the rest of us schmucks is in fact not fucked at all, it is just normal contextualisation, you fool, you absolute buffoon,

        • self@awful.systems
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          Aspiring polymath. Applied R&D @ Privacy and Scaling Explorations #maker #Ethereum🦇🔊🐼🐍🟨🦀 Trying to make the internet better. Opinions are my own and subject to change

          of fucking course

      • corbin@awful.systems
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        Money is power and the powerful already get enough influence over us through other means. We shouldn’t directly listen to them, and in fact we should be skeptical of their claims.

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    Takes like this are one of the many things I pull out to point out how naive and misguided most x-risk obsessive people are. And especially Mr. Altman.

    Despite wide fears of synthetic gain of function attacks, as it turns out, it’s actually really hard to create a new virus meaningfully stronger than the standard endemic ones that already exist. Many countries and labs have legitimately tried. Lots of papers and research. It’s, really really hard to beat nature at the microbiological scale; Viruses have to not only be virulent, but it has to contend with extremely unpredictable intermediate environments. The current endemic viruses got there through many mutations and adaptations inside environments that they were already at least successful (and not in vitro). And in the end, what would be the point? Once a virulent virus breaks out, you have very little control. Either it works really well and backfires or, even far more likely, it doesn’t do that much at all, but it does piss other nations off.

    It’s not impossible. But honestly, yeah, I don’t comprehend x-riskers who obsess over this.

    • Soyweiser@awful.systems
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      How dare you! Eternal torture in Virokos basilisk for you!

      A second minor side point which shows you are prob right on this front, and which broadens it from the risks of biological warfare (which I would argue would be the reason to do research to this) are low to the risk from biological warfare and chemical warfare are low: Soldiers have beards again.

      Now I know, that sound absolutely crazy as an argument. But iirc the reason soldiers were no longer allowed beards around the world wars era was due to gasmask (the pandemic also showed that facial hair make fitting masks hard). But nowadays beards are more and more allowed (and in the case of authoritarian militaristic societies a sign of their elite special forces ;) ))

      To me this shows that at least on the military level they don’t really worry about the risks of artificial (wait, why do they say synthetic? Wouldn’t artificial be a better word? Is this some sort of signaling thing? Anyway) viral attacks in the near future.

      But I could be wrong, just found it interesting, and somewhere some military theorist is prob screaming after reading this, this close to warthunderforuming this place.

  • tetris11@lemmy.ml
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    Wait, I’ve been out for a bit - what was the actual consensus on Covid? I genuinely thought there was a Wuhan Lab that this all originated from?

    I’m not a nut job, I can be reasoned with, i just need to update my beliefs with new info

    • gerikson@awful.systems
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      I believe the scientific consensus is that it originated in a wet market in Wuhan.

      The “lab leak theory”, while not impossible, is also shorthand for a morass of conspiracy theories grounded in racist attitudes towards China. It somehow conflates that the pandemic is China’s fault, if not an outright attack from China, while simultaneously downplaying any efforts to mitigate such an attack.

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        The racist connotations about the lab I knew about, but I didn’t think it made it less true.

        That being said, I just checked wikipedia:

        Most scientists agree that, as with many other pandemics in human history,[1][2][3] the virus is likely derived from a bat-borne virus transmitted to humans via another animal in nature or during wildlife trade such as that in food markets.[11] Many other explanations, including several conspiracy theories, have been proposed.[12][13][14] Some scientists and politicians have speculated that SARS-CoV-2 was accidentally released from a laboratory. This theory is not supported by evidence.[15]

        SARS-CoV-2 has close genetic similarity to multiple previously identified bat coronaviruses, suggesting it crossed over into humans from bats

        https://en.m.wikipedia.org/wiki/Origin_of_COVID-19

        and I think I remember seeing a study that showed the similarity of the sequence to other known sequences and it wasn’t that dramatic a change.

        • self@awful.systems
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          The racist connotations about the lab I knew about, but I didn’t think it made it less true.

          this is an absolute fuck of a sentence and seeing as how you keep JAQing off in a way that platforms conspiracy bullshit, you can just fuck off too

        • inspired@kbin.social
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          In the absence of any actual evidence, it does make it less true. Believing otherwise means ignoring all the obvious (but admittedly circumstantial) evidence that racism is super-fucking-popular. So Occam’s Razor says if two theories have equal levels of zero evidence and one is inherently appealing to lizard brain, that one will gain prevalence so if you want to correct for that bias you have to bias in the opposite direction. How hard? Roll dice.

      • Nihilistra@lemmy.world
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        But would the world Powers have said something if it was an escaped virus out of the Chinese Lab in Wuhan?

        I don’t think it’s a coincidence that the wet market is 20 mins from a lab working on bats and viruses.

        You have a global Pandemic, but also a big part of the population wants revenge because the Chinese can’t keep their lab viruses contained and killed grandma with covid, quite a spicy meatball there.

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          Of course the labs location isn’t a coincidence. They built the lab that studies corona viruses near a huge natural reserve of bats infected with corona viruses.

        • Unaware7013@kbin.social
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          but also a big part of the population wants revenge because the Chinese can’t keep their lab viruses contained and killed grandma with covid, quite a spicy meatball there.

          A shockingly large portion of the population is dumb and refuses to listen to reality, so it’s no surprise they believe in a big bad ruining their 2020s and killing grandma rather than just dumb bad luck with a new virus.

          Let’s also not forget that we also had a large amount of people who refused to do basic COVID prevention techniques like masking, so I’m betting the venn diagram here is pretty close to a circle…

      • MataVatnik@lemmy.world
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        I guess most people aren’t up to date with this subject. There has been plenty of discussion with experts that point to the possibility of a lab leak. The wet market hypothesis has so many holes in it that it’s impossible to take seriously.

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          The wet market hypothesis has so many holes in it that it’s impossible to take seriously.

          Such as?

          • qdJzXuisAndVQb2@lemm.ee
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            Trust me bro! Idk lol

            That kind of comment is useless. Huge claim, zero follow-through. There may well be a workable theory, but that poster has no fucking clue.

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        grounded in racist attitudes towards China

        I don’t understand why that’s considered racist? Why is a conspiracy theory that China has a world class biolab capable of a global pandemic racist?

        A crazy conspiracy that a foreign power has biotech superiority isn’t racism.

    • emergencyfood@sh.itjust.works
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      There is an institute of virology in Wuhan, but it is most likely that Covid-19 spread naturally from bats to humans.

      • Bat coronaviruses are common in the South China - Thailand - Myanmar region, and viruses jump host species all the time.

      • Labs that handle human pathogens are maintained under very high security. The one in Wuhan is BSL4, the highest security rating, and had prior experience handling coronaviruses. Also, the viruses themselves would be marked with radioactive isotopes. Even if they somehow got out of the building, it would be possible to find and quarantine all those exposed to it.

      • If it was released on purpose, then we can narrow the list of suspects down to the countries that can reliably make bioweapons and antidotes with close to 100% certainty. That’s the US, China and maybe Russia. The US and Russia were among the worst affected, and China wouldn’t have released the virus in China.

      So the most likely explanation is that it is a bat virus that jumped hosts.

      • Evinceo@awful.systems
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        the viruses themselves would be marked with radioactive isotopes.

        Is that true? Once the virus replicated in a cell, the new copies wouldn’t be tagged, right?

        • emergencyfood@sh.itjust.works
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          The new ones wouldn’t. But the original radioactive atoms would still be in your body, and they can be detected (within a reasonable amount of time).

          Edit: But if the new viruses infect another person, they wouldn’t have the radioactivity. So usually, in case of a leak, the plan would be to quarantine anyone exposed to the viruses (as detected by radioactivity) and anyone who has been with them that day.

          • Evinceo@awful.systems
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            For the lab leak theory to work you have to assume not only that some workers at the lab got infected, but also that they spread it all over the city before anybody noticed, such that by the time anyone did notice, they were several degrees of contact from the lab workers.

          • Andrew Wade@hachyderm.io
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            @emergencyfood @Evinceo Naw. People have some radioactive atoms in their bodies all the time. But the viruses are marked in another way: they have particular genetic sequences. And with the march of technology the Wuhan Institute of Virology would have sequenced the viruses they were studying and been able to compare the sequences on file with the Covid-19 pathogen.

      • Ibex0@lemmy.world
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        the viruses themselves would be marked with radioactive isotopes. Even if they somehow got out of the building, it would be possible to find and quarantine all those exposed to it.

        China wouldn’t have released the virus in China

        You don’t know that. Nobody knows that, because China destroyed all the evidence. If this was true, they could have proved it, they could have shown the world! “Behold our innocence!!” Why didn’t that happen?

        • Shitgenstein1@awful.systems
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          because China destroyed all the evidence.

          lmao, if you don’t have evidence for X, you don’t have evidence that X is being suppressed. You just lack evidence.

        • zogwarg@awful.systems
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          One (simpler) explanation is that proving an absence of something is almost impossible, and that attempting too hard would make them look a heck of a lot guilty.

          There is a good reason why the burden of evidence is “innocent until proven guilty”, and yes this extends to the (in your eyes) untrustworthy.

          Prove to me you never stole candy from a store as a child (or if you did, replace that accusation with any item of higher value until you hit something you did not steal)

          • Soyweiser@awful.systems
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            There is also the whole ‘why would we have to prove anything? We are fucking China!’ stance all big hegemonic countries have.

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              It’s not just big hegemonic countries in general but specifically the particularly image-obsessed character of geopolitics in East Asia. Mianzi is a real concern in Chinese diplomacy.

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          You don’t know that.

          Yes, but we can reason based on what we know.

          If this was true, they could have proved it, they could have shown the world! “Behold our innocence!!” Why didn’t that happen?

          Most likely the municipality were trying to cover up corruption in the regulation of the wet markets. Maybe they ignored health and safety laws in return for bribes, and didn’t want that to come out.

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      In come the posters who never posted here before to explain that the leak theory is true!

      While I have no real input re the whole lab leak conspiracy theory, I do have a fun anacdote from then. I remember pretty quickly after the lab leak option was dropped somebody came with proof for it saying ‘we have the telephone data, and the day virus started all the telephones from the lab stayed in one place clearly manipulated!’. This story has a few holes, note first the whole ‘we have the telephone data’ which is already weird (esp as china refused to cooperate), then also we don’t have just one day, perhaps this behavior of phones in a lab is normal. Almost like people are forced to put their personal phones in storage when they suit up (iirc often standard practice in those kinds of rooms). Of course the person bringing up the phones theory didn’t think about this. I knew we were in for a wild ride of conspiracies after that one, as it was ‘throw stuff at the wall and see what sticks’ contrarian theories land. (a thing you often see after a tragedy happens, extremely common in far right circles when the far right does an atrocity, where it is often sort of ingroup signal and signal of cruelty). Anyway, that is just an interesting thing I remembered which I wanted to share, on the subject at hand my opinion is I doubt it was a lab leak, but I also don’t think we will ever know for sure, and also we will never find enough evidence that it wasn’t a lab leak to convince the people who convinced themselves it was one.

    • Blapoo@lemmy.ml
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      I’m on your page at least - best evidence we had was that it leaked from a Wuhan lab.

      Not sure what the conspiracy here is, other than “Rich man has thoughts that come close to an opinion on vaccines. Get the pitchforks!”

      Missing the forest for the trees, it feels like - The man has a good point about synthetic viruses.

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    This sounds like a bad take, but for good reasons. I would like the people making AI to take really, really seriously the potential of synthetic viruses. It sounds like he’s doing that (rather than working backwards from racism).

    • Soyweiser@awful.systems
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      As often is the case here on awful systems, both sides are bad. Matt Ridley is a climate change denying shouty british aristocrat person all mad that greenpeace is not admitting there is a possibility windmills might be affecting whales (71 dead ones in the uk last year, no idea about the average of dead wales) (iirc according to research it isn’t the windmills it is the increased and intensified ship traffic), if you were wondering why the article is written so badly that it seems like it is written by a dark side sneerclub commenter (aka a focus more on funny sneers than making an solid case, which is fine for this silly site, but he is pretending to be a science reporter).

      (Taking the risks of viruses (whatever their origin) is good of course, just deciding that covid is synthetic is sneerworthy, as is only focusing on synthetic viruses because handwave AGI intelligence is magic).

      Also note that Matt wrote a book arguing that covid came from a lab, so this article is also just book promotion. (he is also of course, a libertarian).

  • AMillionNames@sh.itjust.works
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    There’s a good possibility that it was due to a lab leak, but it doesn’t necessarily have to be synthetic. This was a lab taking too many liberties handling a virus that was already at risk of making the jump to humans, is it “lab-leak covid truther” to claim the inevitable under those circumstances would happen?

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    “Synthetic” and “lab leak” are not mutually exclusive. It could have been either, neither, or both.

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    Everyone who is saying virus spread from bats to humans - you do realize there were people researching on bats in Wuhan, right? If it’s from a bat, that doesn’t automatically mean from a bat in nature.

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    Is there any evidence he was fired for these beliefs? Using the deliberately vague phrase, “earlier this year” in November gives the impression of an author trying to either manufacture causation where none exists.

    The only part of this article about Altman is the beginning. This author seems incredibly passionate about virology and is using recent news to draw attention to the author’s points on the subject.

    • Architeuthis@awful.systemsOP
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      So far I like best that he was probably fired for not being enough of an AI doomer, i.e. deprioritizing AI safety and diverting too many resources from research to product service, all the while only paying lip service to the ea/rationalist orthodoxy about heading off the impending birth of AI Cthulhu.

      Any remaining weirdness can be explained away by the OpenAI board being sheltered oddballs who honestly though they could boot the CEO and face of the company on a dime and without repercussions, in order to bring in an ideologically purer replacement.

      • Architeuthis@awful.systemsOP
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        ‘We are the sole custodians of this godlike technology that we can barely control but that we will let you access for a fee’ has been a mainstay of OpenAI marketing as long as Altman has been CEO, it’s really no surprise this was ‘leaked’ as soon as he was back in charge.

        It works, too! Anthropic just announced they are giving chat access to a 200k token context model (chatgtp4 is <10k I think) where they supposedly cut the rate of hallucinations in half and it barely made headlines.

  • feedum_sneedson@lemmy.world
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    I think it’s a fairly credible claim, that the coronavirus originated in a lab. There’s been leaks in the past, of similar pathogens - once in the USA and once in Taiwan, I think. Not a very interesting conspiracy theory. Equally, animal agriculture is ripe for the development of zoonoses, regardless of the country. I don’t think it’s especially important, ultimately, unless it informs better practices in both areas.

      • self@awful.systems
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        I’m waiting for them to post something relevant to Sam Altman or you know maybe just a general techtake???

        I know I’m gonna be disappointed

        • froztbyte@awful.systems
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          Couldn’t even be bothered to make some tortured Tolkien, only an oblique reference

          Let’s see…

          All that is gold does not glitter
          Not all those who wander are lost
          The post that is strong does not wither
          These others’ posting remain a cost
          

          Merely 3 minutes of idle thought! Imagine how many GPUs I could’ve 10tok/s’d for it! Oh the humanity

          e: fuck you lemmy, give me newlines

        • feedum_sneedson@lemmy.world
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          Maybe turn this into a private group if you’re bothered. For whatever reason this thread has appeared on Top Everything, so that’s where your visitors are coming from.

            • self@awful.systems
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              still boggling at the high degree of redditor logic behind “this thread appeared on my screen therefore I’m welcome to post my garbage in it”. I can’t decide if it’s better or worse than the couple of r/SneerClub threads demanding that SneerClub never appear on the poster’s Reddit homepage ever again