Not a fan of spinoffs just for the sake of it but… A star trek series set up in the earliest stages of human interspace travel (akin to the tales of his family) would be so interesting. Not necesserily focused on Mayweather, but surely with his presence. No federation in sight, just starfleet being a couple of cargos in space barely surviving with little technology and a lot of hope.

And lots of ghost stories of course. Space is new for humans and very scary.